The Advanced Computation Group (ACG) of Apple Computers is a division that researches applications for software on Apple technology. ACG concentrates on Mac OS X for scientific applications, vectorization, tutorials, algorithm implementations for specific Apple products and joint R&D with outside partners.

Projects include Apple/Genentech BLAST (an algorithm for comparing biological sequences, such as the amino-acid sequences of different proteins) which runs several times faster on Power Mac and Xserve than generic BLAST runs on other platforms. This implementation is open source software developed in cooperation with genentech. Xgrid is clustering software for scientific researchers, allowing distributed computing.